Alopecia in Women, Androgenetic Alopecia

Alopecia may be divided into problems wherein the hair follicle is everyday however the biking of hair boom is strange and problems wherein the hair follicle is damaged. Androgenetic alopecia is the maximum not unusualplace motive of hair loss in girls. Other problems consist of alopecia areata, telogen effluvium, cicatricial alopecia, and worrying alopecias. The prognosis is normally primarily based totally on a radical records and a centered bodily exam. In a few patients, decided on laboratory assessments or punch biopsy can be necessary. Topically administered minoxidil is classified for the remedy of androgenetic alopecia in girls. Corticosteroids and different sellers are usually utilized in girls with alopecia areata. Telogen effluvium is usually a self-constrained disorder. Because alopecia may be devastating to girls, control need to consist of an evaluation for psychologic consequences.

 

Although alopecia can arise everywhere at the frame, it's miles maximum distressing whilst it influences the scalp. Hair loss can variety from a small naked patch this is without problems masked through hairstyling to a greater diffuse and apparent sample. Alopecia in girls has been discovered to have appreciably deleterious consequences on self-esteem, psychologic well-being, and frame image.1,2

 

Pathophysiology

Every hair follicle usually is going thru 3 phases: anagen (boom), catagen (involution, or a quick transition among boom and resting), and telogen (resting).three Disorders of alopecia may be divided into the ones wherein the hair follicle is everyday however the biking of hair boom is strange (e.g., telogen effluvium) and people wherein the hair follicle is damaged (e.g., cicatricial alopecia).

 

Diagnosis

A cautious records frequently indicates the underlying motive of alopecia. Crucial elements consist of the period and sample of hair loss, whether or not the hair is damaged or shed on the roots, and whether or not dropping or thinning has accelerated. The patient's diet, medications, gift and beyond scientific conditions, and own circle of relatives records of alopecia are different critical elements.

 

The bodily exam has 3 components. First, the scalp is tested for proof of erythema, scaling, or irritation. Follicular gadgets are obvious in nonscarring alopecias however absent in scarring types. Second, the density and distribution of hair are assessed. Third, the hair shaft is tested for caliber, duration, shape, and fragility.4

 

The “pull check” is an smooth method for assessing hair loss. Approximately 60 hairs are grasped among the thumb and the index and center fingers. The hairs are then lightly however firmly pulled. A bad check (six or fewer hairs obtained) shows everyday dropping, while a wonderful check (greater than six hairs obtained) shows a procedure of energetic hair dropping. Patients need to now no longer shampoo their hair 24 hours earlier than the check is performed.4

 

If the prognosis isn't clean primarily based totally at the records and bodily exam, decided on laboratory assessments and, on occasion, punch biopsy can be indicated. A stepwise method to the prognosis of hair loss is supplied in Figure 1.five,6

 

Androgenetic Alopecia

Androgenetic alopecia, or hair loss mediated through the presence of the androgen dihydrotestosterone, is the maximum not unusualplace shape of alopecia in guys and girls. Almost all men and women have a few diploma of androgenetic alopecia.7 The hair loss normally starts among the a long time of 12 and forty years and is regularly inadequate to be noticed. However, seen hair loss takes place in about one 1/2 of of all men and women through the age of fifty years8 (Figure 2). In girls, hairstyling may also masks early hair loss.

 

View/Print Figure

 

 

 

FIGURE 2.

 

Androgenetic alopecia.

 

Hair follicles comprise androgen receptors. In the presence of androgens, genes that shorten the anagen segment are activated, and hair follicles cut back or emerge as miniaturized. With successive anagen cycles, the follicles emerge as smaller (main to shorter, finer hair), and nonpigmented vellus hairs update pigmented terminal hairs. In girls, the thinning is diffuse, however greater marked withinside the frontal and parietal regions. Even men and women with excessive androgenetic alopecia nearly continually have a skinny edge of hair frontally. The last hair configuration may also resemble a monk's haircut.

 

Women with androgenetic alopecia do now no longer have better tiers of circulating androgens. However, they were discovered to have better tiers of 5α-reductase (which converts testosterone to dihydrotestosterone), greater androgen receptors, and decrease tiers of cytochrome P450 (which converts testosterone to estrogen).6

 

Most girls with androgenetic alopecia have everyday menses, everyday fertility, and everyday endocrine function, which include gender-suitable tiers of circulating androgens. Therefore, an in depth hormonal work-up is unnecessary. If a female has abnormal menses, abrupt hair loss, hirsutism, or zits recurrence, an endocrine assessment is suitable. In this situation, general testosterone, unfastened testosterone, dehydroepiandrosterone sulfate, and prolactin tiers need to be obtained.6

 

Because the hair loss in androgenetic alopecia is an aberration of the everyday hair cycle, it's miles theoretically reversible. Advanced androgenetic alopecia, however, won't reply to remedy, due to the fact the irritation that surrounds the bulge region of the follicle may also irreparably harm the follicular stem cell.

 

TREATMENT

Minoxidil (Rogaine)

The presently desired remedy for androgenetic alopecia is topically administered 2 percentage minoxidil.6,eight,nine Minoxidil seems to have an effect on the hair follicle in 3 ways: it will increase the duration of time follicles spend in anagen, it “wakes up” follicles which might be in catagen, and it enlarges the real follicles. The mechanism through which minoxidil consequences those adjustments isn't known. Vellus hairs amplify and are transformed to terminal hairs. In addition, dropping is reduced.

 

In a randomized, controlled, double-blind scientific trial regarding 550 girls 18 to forty five years of age, remedy with 2 percentage minoxidil answer ended in a better hair depend in comparison with placebo.10 [Evidence label A, randomized controlled trial] In any other study,eleven 50 percentage of girls dealt with with 2 percentage minoxidil had at the least minimum hair regrowth, and thirteen percentage had slight regrowth. No appreciably accelerated gain has been proven for the five percentage minoxidil answer in comparison with the two percentage answer.eight The U.S. Food and Drug Administration (FDA) has classified topically administered minoxidil for the remedy of androgenetic alopecia. A dropper is used to use minoxidil answer without delay onto dry scalp two times daily. After every use, fingers need to be washed very well to keep away from inadvertent software to different components of the frame. Minoxidil is indexed as a being pregnant class C drug. It isn't endorsed to be used in men and women more youthful than 18 years.

 

The number one facet impact of topical minoxidil remedy is hypertrichosis (immoderate hair boom). The hair boom is most customarily stated above the eyebrows, withinside the malar region, and at the lateral cheeks. It on occasion takes place above the higher lip and at the chin. Facial hypertrichosis has been suggested to have an effect on three to five percentage of girls dealt with with the two percentage answer and greater than five percentage of girls dealt with with the five percentage answer.eight

 

Hypertrichosis disappears after a year, inspite of persevered use of minoxidil, and remits inside one to 6 months if remedy is stopped.eight Bleaching of longer, darker hair is useful cosmetically. Hair elimination methods are seldom necessary. Explanations for the prevalence of this facet impact consist of neighborhood intravascular unfold of minoxidil, inadvertent guide switch of the drug to the face, and transmission of residual minoxidil from pillows.eight

 

Commercial arrangements comprise minoxidil in a propylene glycol base. Allergic reactions to this base restriction the usefulness of minoxidil remedy in a few girls. A compounding pharmacist can put together an opportunity guidance wherein minoxidil is suspended in a much less sensitizing agent inclusive of polyethylene glycol.12

 

Exogenous Estrogen

In the beyond, exogenous estrogen changed into used to deal with androgenetic alopecia. This remedy is used much less frequently now, due to the fact minoxidil is greater powerful. In fertile girls with androgenetic alopecia who request oral contraception, it's miles critical to pick out a tablet containing the least androgenic progestin, inclusive of norgestimate (in Ortho-Cyclen, Ortho Tri-Cyclen), norethindrone (in Ovcon 35), desogestrel (in Mircette), or ethynodiol diacetate (in Demulen, Zovia).eight

 

Spironolactone (Aldactone)

This drug is a vulnerable aggressive inhibitor of androgen binding to androgen receptors. It additionally decreases the synthesis of testosterone. For those reasons, orally administered spironolactone has been attempted withinside the remedy of androgenetic alopecia, despite the fact that questions continue to be approximately its usefulness. Spironolactone may be useful in girls who additionally have hirsuitism.thirteen However, the FDA has now no longer classified this drug for the remedy of androgenetic alopecia.

 

Finasteride (Proscar)

This agent has been proven to be powerful in guys with alopecia. However, finasteride need to now no longer be utilized in girls of childbearing age, due to the fact 5α-reductase inhibitors may also motive abnormalities of the outside genitalia withinside the male fetus. Moreover, finasteride has now no longer been proven to be beneficial in postmenopausal girls with androgenetic alopecia.eight

 

Tretinoin (Retin-A)

Topical tretinoin remedy as an accessory to minoxidil has proven a few promise.6,14

 

Other Treatments and Hair-Care Practices

When hair loss is extensive, wigs can be worn. The use of minigrafts, instead of large plugs, in hair transplantation affords a greater cosmetically attractive outcome.15

 

Hairstyling, teasing, coloring, permanents, and the usage of hair spray are supported, instead of prohibited, as manner of managing the beauty consequences of androgenetic alopecia. Women may also shampoo their hair as regularly as they desire with out worry of worsening hair loss.eight

 

Alopecia Areata

Alopecia areata is patchy hair lack of autoimmune origin7 (Figure three). It normally affords as a unmarried oval patch or more than one confluent patches of asymptomatic, well-circumscribed, non-scarring alopecia. Severity varies from a small naked patch to lack of hair at the complete scalp. So-called “exclamation point” hairs are a trademark of the disorder. These hairs are normally positioned on the outer edge of the patch and expand numerous millimeters above the scalp.16

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Turkey’s #1 Hair Restoration Experts

15 Years experience in hair transplantation. Professional medical hair restoration. #wecare


Fue Hair Transplant


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Beard and Mustache Transplantation


Hair Transplantation by Turkey Hair Expert


Turkey Hair Expert provides high quality and safe hair transplant in Turkey at its contracted premier clinic, using the most advanced techniques and technologies. With a patient-centric and ethical approach, Turkey Hair Expert offers high-quality hair transplantation in Turkey with its experienced doctors and medical team.

For 3 years we have been chosen as the best hair transplant clinic in Istanbul (2016-2017-2018). Since our foundation we have dedicated all our knowledge and skills to hair transplantation, becoming true leaders in the sector.

As Turkey Hair Expert we are proud to offer competence and professionalism to patients from all over the world, who choose the experience of Dr.Emine Karabash, Dr.Mustafa Yilmaz and the highly qualified team of professionals.

Our Team

A team of professionals dedicated to your well-being. Hair transplantation is an art: it requires solid knowledge, undeniable technical expertise and an artistic eye. But your stay doesn't end with your hair transplant session. The administrative team welcomes you and remains at your disposal throughout the day to make sure you have a good time, in complete confidence and relaxation.The team in operation has an experience of at least 5 years and maximum 15 years.


Mustafa Yilmaz


My vision of hair transplantation is totally in line with this perspective: to be at the service of regained well-being through effective techniques that give natural results. The hair, in women of course, but in men, it is the force of life, it is the finery. Losing them is truly an injury, a trauma. It’s terrible!

Also, I enjoy listening to my patients and never judging them. I am then able to give them the best advice and allow them to regain their self-confidence.

I naturally surrounded myself with a caring, expert and extremely rigorous team in its field to be sure to offer men and women who suffer from baldness solutions that work, without ever ignoring safety and reliability.

The used techniques depend on Dr. Mustafa Yilmaz decision after doing the medical diagnosis, Choi Pen / DHI - Sapphire - Micro FUE are used normally in our operations.

Emine Karabash


I started dermatology almost 15 years ago now and thanks to my encounters with other dermatologists, I quickly turned to medical aesthetics.

More and more women and men want to feel good about their hair, and when this is the case, one gains confidence in oneself, in everyday life, in social life and in work.

I have also always remained "classic", in this movement that is now called the "Soft touch", namely to privilege discretion, elegance, and of course, naturalness. Not ostentatious! I prefer to repair what is damaged, rather than change or modify.

The used techniques depend on Dr Emine’s decision after doing the medical diagnosis, Choi Pen / DHI - Sapphire - Micro FUE are used normally in our operations.

Ayshe Yalchin


She is the one who sees you in consultation and who makes the diagnosis. On D-Day, Ayse. starts the procedure with local anesthesia in your donor area. She is present throughout your intervention, ensuring its perfect completion, with the support of her team of experts.

Testimonial


At first I had some nerves surrounding the procedure, however, these were soon gone when reassured by the professional staff. So much so I came back for a second hair transplant. The procedure was painless and was completed on the same day, allowing for visible results with minimal scarring.

 

- James Elliott -

 

I came to Turkey Hair Expert clinic for hair transplant. From the start to finish everything was very professional. I received great service. The experience was outstanding.

 

- Allen Jones -

 

I recently underwent a hair transplant with Turkey Hair Expert and the care and attention that I received were outstanding. They cover everything for you and booked everything but the flights. They are all extremely friendly and make you feel welcome from start to finish. Definitely, recommend.

 

- Wayne Bennett -

 

I travelled to Turkey for a hair transplant with Turkey Hair Expert and was blown away by the facilities and the caring staff that were there upon my arrival. The result I am beginning to see are amazing and have fully restored my confidence. Definitely my top recommendation.

 

- Angar Safi -

 

I found out about the services provided by Turkey Hair Expert through a friend who had previously had the procedure done with them. I found the service to be highly professional with high-quality results, I would recommend this service to anyone.

 

- Oliver Lewis -

 

Turkey Hair Expert has helped to make the hair transplant more affordable to those who need them and the staff are amazing. They are on hand every step of the way and will answer any questions that you may have. – Definitely, recommend this service to all.

 

- Darren Thomas -

 

I came to Turkey to have a hair transplant with Turkey Hair Expert. I had a large number of graphs done and the time flew by. The process was seamless with an extremely high level of care. I highly recommend this service to all. Thanks, Longevita.

 

- Leon Hazlewood -

 

The overall experience with Turkey Hair Expert has exceeded my expectations. The surgery was painless and undergone in a professional manor and the results are outstanding. Extremely happy!

 

- David Miller -

 

I could not be happier with the results of my FUE hair transplant. The experience was outstanding and the accommodation, as well as the overall location, was beautiful. Definitely, use this service for a hair transplant!

 

- Kirk Trow -

 

I am absolutely satisfied with the procedure and the outcome visible so far. The communication and consultation with Turkey Hair Expert was very friendly and clear from the beginning to the end.

 

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Great experience. Staff is friendly and professional. Everything was taken care of from the moment we arrived at the airport till the day we left. Highly recommend!

 

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Before & After


Hair Transplantation & Methods


DHI Hair Transplant

The DHI hair transplantation method, which is called direct hair implant, is performed by implanting the follicles using a special tool with fine-tipped needles.

DHI Hair Transplant

The DHI hair transplantation method, which is called direct hair implant, is performed by implanting the follicles using a special tool with fine-tipped needles.

While performing this process, there is no incision or stitch scar at all. The purpose of this transplantation method is to minimize the time that the hair follicles stay outside and place the follicles with a good density and continuously.

Fue Hair Transplant

With the FUE method (Follicular Unit Extraction), the hair follicles are taken one by one with a special micro-motor and the aid of local anesthesia.

FUE Hair Transplant

With the FUE method (Follicular Unit Extraction), the hair follicles are taken one by one with a special micro-motor and the aid of local anesthesia; grafts are repositioned afterwards in the bald areas, according to the angle and the natural direction of hair growth.

Generally the donor area (the area from which the follicles are taken) is the back of the head. Since the nape follicles are genetically stronger and more resistant to shedding, this region is preferred as a donor area. However, if the area is not dense enough, grafts are collected from other parts of the body.

Sapphire Fue Hair Transplant

Although the Sapphire Fue hair transplantation method is not much different from other transplantation methods.

Sapphire Fue Hair Transplant

Although the Sapphire Fue hair transplantation method is not much different from other transplantation methods, with this technique the micro channels are opened by fine tips of sapphire, a precious stone.

On the contrary, in classical fue, the process is performed by metal slit. Likewise, after the follicles are taken one by one from the donor area, they are carefully placed according to the direction and angle of the hair.

Beard and Mustache

Beard and mustache transplantation is a procedure designed for those with a loss of beard or mustache.

Beard and mustache transplantation

Beard and mustache transplantation is a procedure designed for those with a loss of beard or mustache. Beard and mustache are an important part of a man’s appearance, as much as their hair.

This method is recommended in cases of hair loss caused by the testosterone hormone, for those with thinning beard hair wishing to have a bushy beard. It is possible to get a healthy and natural look of the beard by undergoing a beard transplant operation.

FUE Titanium Technique



   FUE Titanium Technique


  Lifetime warranty letter


  Free Transfers


  Complimentary 3 nights / 4 days, hotel accommodation incl. breakfast


  Translator


   Blood Tests


  Washing and Control


  Medications box after the operation


  Plasma injection


  Checking the grafts using a Microscope device


  Local Anesthesia for painless operation process


  Laser Therapy


  Ice grafts feeding device


  Treatment and vitamin box

Sapphire FUE Technique



   Sapphire FUE Technique


  Lifetime warranty letter


  Free Transfers


  Complimentary 3 nights / 4 days, hotel accommodation incl. breakfast


  Translator


   Blood Tests


  Washing and Control


  Medications box after the operation


  Plasma injection


  Checking the grafts using a Microscope device


  Local Anesthesia for painless operation process


  Laser Therapy


  Ice grafts feeding device


  Treatment and vitamin box

DHI Technique



   DHI Technique


  Lifetime warranty letter


  Free Transfers


  Complimentary 3 nights / 4 days, hotel accommodation incl. breakfast


  Translator


   Blood Tests


  Washing and Control


  Medications box after the operation


  Plasma injection


  Checking the grafts using a Microscope device


  Local Anesthesia for painless operation process


  Laser Therapy


  Ice grafts feeding device


  Treatment and vitamin box

  Get a free online consultation
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